Can anything be real without being observed? Can that question ever be answered? I don't know, but it doesn't matter.
The perception of reality is enough to make predictions about how I and other conscious beings will perceive it in the future. I don't care what is "really" going on; science is exceedingly good at understanding everything that touched and interacts without perception, so why would you need anything else? Of course, religious people like to differ. To me, they always seem to be making useless hypotheses.